| Achievement/Trophy | Description |
| Fallen Angel | Get your first supernatural powers |
| H-E-... | Complete all open-world gameplay in two districts of the city of New Hades |
| ...Double-hockey-sticks | Conquer all of New Hades with 100% city take over |
| Fly, You Fools | Fly for 250,000 meters |
| The Wings of Angels | Be airborne during supernatural jumps or flight for a combined 10 minutes of gameplay |
| Get Stoned | Stonify and shatter kill 100 demons with the stone blast power |
| Footprints in the Sand | Kill 150 demons with the stomp power |
| Purple Demons | Have minions kill 100 demons with the summon power |
| Oxymoronic | Kill 100 demons using the Coldfire aura power |
| The Seven Deadly Weapons | Kill 25 demons with each of the seven deadly weapons |
| The Devil's Dues | Upgrade one weapon to the max |
| Fell from Heaven | Purchase 113 supernatural power upgrades |
| Plague of Gat | Kill 1000 demons with any combination of powers |
| The King of Hell | Complete ALL of the challenges |
| The Book of More, Man | Find 64 tomes |
| Seraphim and Cherubim | Play for at least 2 hours as Gat and 2 hours as Kinzie |
| Level One Demon | Buy your first upgrade from the upgrade store |
| Hazardous Dukes | Kill 25 Arch Dukes |
| Soul in One | Find 100 soul clusters |
| Soul Drain | Find 100% of all soul clusters |
| My Dear Watson | Choose a new element for all of your powers |
| Epic Flight Quest | Fly from the roof of Snowball's Chance to Sinterpol HQ's roof, without landing |
| Twenty-twenty Vision | Spend over 20 hours in Hell |
| Double Trouble | Play Saints Row: Gat Out of Hell co-op for 3 hours |
| Sloth Love Chunk | Get 250 kills with the Essence of Sloth |
| Nailed It | Get 100 kills with the God's Hammer |
| Shut Your Eyes | Get 250 kills with the Essence of Wrath |
| Imp-fanticide | Kill 50 of your own summoned imps |
| Extra Crispy | Die in the lava |
| Gnarly Wave | Car surf on a comet while it explodes |
| Hell Buoy | Have 5 imps attached to you at one time |
| Top Gunner | Shoot down a spire missile with a blast while hovering |
| Terminal Hog | Take down an extraction facility while on a motorcycle |
| Transcontinental | Fly continuously for 60 seconds |
| Shooting Star | Fly for 500 meters while on fire |
| Put Up Your Dukes | Kill an Arch Duke with a melee attack |
| Out of the Frying Pan | Knock a vehicle into the lava |
| Soft Shoe | Stay in contact with the lava for 10 seconds without dying |
| Cluster Luck | Collect at least 5 soul clusters without touching the ground |
| Let's Bounce | In Torment's Fraud, hit 5 vehicles in a row without touching the ground |
| Are You Crazy? | Get a comet into the Ultor lobby |
| Raise the Roof | Smack into the ceiling 10 times while wall running |
| Barn Burner | Find 75 Barnstorming Diversion locations |
| Saints' Creed | Stand on the tallest mast of the Queen Anne's Revenge |
| Satan Punchers | Beat the game |
